CXCL14

Across TCGA cell cohorts, CXCL14 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,038 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CXCL14-associated GO terms across cancer lineages are Energy derivation by oxidation of organic compounds, Mitochondrial electron transport, cytochrome c to oxygen, and Adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Each is linked with CXCL14 in more than 5 cancer types. Because this analysis shows association rather than direction, both CXCL14-to-partner and partner-to-CXCL14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy derivation by oxidation of organic compounds grouped by CXCL14-low versus CXCL14-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL14→partner) and Y-score (partner→CXCL14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Energy derivation by oxidation of organic compounds →	+0.064	+2.208	<.001	<.001	3	6
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.072	+1.601	.001	.003	3	5
LARGE_INTESTINE	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.028	-1.147	<.001	.001	3	5
KIDNEY	Aerobic respiration →	+0.072	+1.764	.003	.005	2	6
OESOPHAGUS	Proton transmembrane transport →	+0.051	+2.097	.007	.007	3	5
LARGE_INTESTINE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.062	+1.724	.004	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,038 associations by consensus.

Energy derivation by oxidation of organic compounds by CXCL14 expression — LARGE_INTESTINE

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