CXCL11

Across TCGA patient cohorts, CXCL11 protein abundance is significantly associated with the RNA expression of many other genes, with 130 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CXCL11-associated genes across cancer lineages are RNF32, POLE4, and DLEU2L. Each is linked with CXCL11 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL11-to-partner and partner-to-CXCL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CXCL11 versus RNF32 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL11→partner) and Y-score (partner→CXCL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNF32 →	+0.659	+0.420	.001	.004	2	1
BRCA	POLE4 →	-0.839	-0.440	.005	.009	2	1
BRCA	DLEU2L →	+0.355	+0.420	.004	.004	2	1
BRCA	RWDD3 →	+0.635	+0.420	.002	.004	2	1
BRCA	ATP5F1E →	-1.004	-0.438	.008	<.001	2	1
BRCA	HELB →	+0.940	+0.420	.007	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 130 associations by consensus.

CXCL11 vs RNF32 — BRCA

Explore this scatter interactively →