CXCL1

Across TCGA pan-cancer cohorts, CXCL1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CXCL1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CXCL1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CXCL1 expression acts as an unfavorable survival marker.

LUAD, PDAC, and HNSC are the cancer types where CXCL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	III,IV	0.348	0.931	.029	6	view →
PDAC	OS	Quartile	All	0.714	0.878	.046	3	view →
HNSC	DFS	Median	III,IV	0.357	0.748	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CXCL1–LUAD (OS)

Open the LUAD breakdown →