CX3CR1

Across TCGA patient cohorts, CX3CR1 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,495 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CX3CR1-associated proteins across cancer lineages are DOCK4_T1899, FES, and NAIP. Each is linked with CX3CR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CX3CR1-to-partner and partner-to-CX3CR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CX3CR1 versus DOCK4_T1899 in GBM, with a Pearson correlation of 0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CX3CR1→partner) and Y-score (partner→CX3CR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DOCK4_T1899 →	+0.522	+0.997	.001	<.001	3	2
GBM	FES →	+0.442	+0.776	.002	<.001	3	2
GBM	NAIP →	+0.867	+1.114	<.001	.001	3	2
GBM	ARPC1B_S361 →	+0.588	+1.326	.003	<.001	3	1
GBM	ARRDC1 →	+0.352	+0.900	<.001	<.001	3	1
GBM	ATAD2 →	-0.707	-1.101	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,495 associations by consensus.

CX3CR1 vs DOCK4_T1899 — GBM

Explore this scatter interactively →