CX3CR1

Across TCGA cell cohorts, CX3CR1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CX3CR1-associated genes across cancer lineages are SLC15A5 and GZMH. Each is linked with CX3CR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CX3CR1-to-partner and partner-to-CX3CR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC15A5 grouped by CX3CR1-low versus CX3CR1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CX3CR1→partner) and Y-score (partner→CX3CR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SLC15A5 →	+0.023	+5.415	<.001	.004	3	1
CNS	GZMH →	+0.040	+6.357	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SLC15A5 by CX3CR1 expression — LARGE_INTESTINE

Explore this box plot interactively →