CX3CL1

Across TCGA patient cohorts, CX3CL1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,764 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CX3CL1-associated genes across cancer lineages are PPP1R14C, UBE2L3, and HMOX2. Each is linked with CX3CL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CX3CL1-to-partner and partner-to-CX3CL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CX3CL1 versus PPP1R14C in BRCA, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CX3CL1→partner) and Y-score (partner→CX3CL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPP1R14C →	+3.078	+1.420	<.001	.004	3	3
HNSC	UBE2L3 →	+1.373	+1.827	.009	.003	3	2
LSCC	HMOX2 →	+0.301	+0.566	.005	.007	2	3
GBM	HMGCS1 →	+0.527	+0.331	.004	.003	3	2
LSCC	SLC1A4 →	+0.768	+0.609	<.001	<.001	3	2
BRCA	CCDC170 →	-2.280	-1.069	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,764 associations by consensus.

CX3CL1 vs PPP1R14C — BRCA

Explore this scatter interactively →