CX3CL1

Across TCGA cell cohorts, CX3CL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,586 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CX3CL1-associated GO terms across cancer lineages are Negative regulation of hippocampal neuron apoptotic process, Regulation of hippocampal neuron apoptotic process, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with CX3CL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CX3CL1-to-partner and partner-to-CX3CL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of hippocampal neuron apoptotic process grouped by CX3CL1-low versus CX3CL1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CX3CL1→partner) and Y-score (partner→CX3CL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of hippocampal neuron apoptotic process →	+1.501	+2.618	<.001	<.001	3	11
KIDNEY	Regulation of hippocampal neuron apoptotic process →	+1.601	+2.618	<.001	<.001	3	10
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.104	+2.524	<.001	<.001	3	8
BLOOD_Lymphoma	Regulation of myoblast fusion →	+0.084	+1.088	<.001	.008	3	8
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.095	+1.090	<.001	.009	3	8
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.094	+1.090	<.001	.009	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,586 associations by consensus.

Negative regulation of hippocampal neuron apoptotic process by CX3CL1 expression — KIDNEY

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