CX3CL1

Across TCGA cell cohorts, CX3CL1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CX3CL1-associated genes across cancer lineages are CCDC54, ACER1, and WDR87. Each is linked with CX3CL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CX3CL1-to-partner and partner-to-CX3CL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC54 grouped by CX3CL1-low versus CX3CL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CX3CL1→partner) and Y-score (partner→CX3CL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC54 →	+0.117	+3.736	.001	.004	3	1
LARGE_INTESTINE	ACER1 →	+0.117	+3.145	<.001	.004	3	1
LARGE_INTESTINE	WDR87 →	+0.020	+3.353	<.001	.004	3	1
LARGE_INTESTINE	LRRC3C →	+0.285	+3.099	<.001	.004	3	1
LARGE_INTESTINE	USP17L7 →	+0.069	+3.333	<.001	.009	3	1
LARGE_INTESTINE	FAM218A →	+0.371	+2.906	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

CCDC54 by CX3CL1 expression — LARGE_INTESTINE

Explore this box plot interactively →