CWH43

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CWH43 protein abundance is significantly associated with the RNA expression of many other genes, with 4,323 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CWH43-associated genes across cancer lineages are RIC8B, PERP, and ECM1. Each is linked with CWH43 in more than 1 cancer types. Because this analysis shows association rather than direction, both CWH43-to-partner and partner-to-CWH43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CWH43 versus RIC8B in HNSC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CWH43→partner) and Y-score (partner→CWH43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRIC8B →-0.570-0.570.003.00432
HNSCPERP →+1.123+0.859.005<.00132
HNSCECM1 →+1.666+0.793<.001<.00132
UCECCKAP2L →-0.973-0.995.004<.00132
UCECCLK2 →-0.676-0.799<.001.00432
HNSCTPI1P4 →+0.863+0.693<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,323 associations by consensus.

CWH43 vs RIC8B — HNSC

Per-sample scatter of CWH43 vs RIC8B in HNSC (Pearson r = -0.47).

Explore this scatter interactively →

Exploration