CWF19L2

Across TCGA patient cohorts, CWF19L2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CWF19L2-associated genes across cancer lineages are Cyclin-B1, ASNS, and Caspase-7-cleavedD198. Each is linked with CWF19L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CWF19L2-to-partner and partner-to-CWF19L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cyclin-B1 grouped by CWF19L2-low versus CWF19L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CWF19L2→partner) and Y-score (partner→CWF19L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.734	+2.584	<.001	<.001	3	3
UCEC	ASNS →	+0.550	+2.906	<.001	.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.503	+1.604	.011	.021	3	2
UCEC	14-3-3_beta →	-0.084	-2.088	.012	.016	3	1
UCEC	ACC1 →	+0.324	+2.335	.007	.018	3	1
UCEC	MEK1 →	+0.436	+3.999	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Cyclin-B1 by CWF19L2 expression — UCEC

Explore this box plot interactively →