CWF19L2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CWF19L2 mutation is significantly associated with the RNA expression of many other genes, with 601 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CWF19L2-associated genes across cancer lineages are INSM2, TFDP3, and TCP11X2. Each is linked with CWF19L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CWF19L2-to-partner and partner-to-CWF19L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSM2 grouped by CWF19L2-low versus CWF19L2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CWF19L2→partner) and Y-score (partner→CWF19L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaINSM2 →+0.182+3.769<.001.00832
BLOOD_LeukemiaTFDP3 →+0.009+4.269<.001.00232
BLOOD_LeukemiaTCP11X2 →+0.139+4.060<.001.00332
LARGE_INTESTINEEARS2 →+0.442+2.850.001<.00132
LARGE_INTESTINETTC19 →+0.716+3.459<.001<.00132
LARGE_INTESTINECEPT1 →+0.481+2.459<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 601 associations by consensus.

INSM2 by CWF19L2 expression — BLOOD_Leukemia

Box plot of INSM2 in CWF19L2-low vs CWF19L2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration