CWF19L1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CWF19L1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CWF19L1 data layer compared with 21 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CWF19L1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CWF19L1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

COAD, LSCC, and LUAD are the cancer types where CWF19L1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianIV0.4930.944.03118view →
LSCCDFSMedianII,III,IV1.0000.419.0088view →
LUADDFSMedianAll0.9670.833.0111view →
PDACDFSMedianIII,IV0.4880.940.0241view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CWF19L1–COAD (DFS)

Kaplan–Meier survival curve for CWF19L1 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration