CWF19L1

Across TCGA patient cohorts, CWF19L1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CWF19L1-associated genes across cancer lineages are MEK1, TSC1, and GSK3-a-b. Each is linked with CWF19L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CWF19L1-to-partner and partner-to-CWF19L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by CWF19L1-low versus CWF19L1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CWF19L1→partner) and Y-score (partner→CWF19L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.373	+2.999	.023	.035	3	2
UCEC	TSC1 →	-0.193	-2.000	.012	.032	3	2
UCEC	GSK3-a-b →	-0.143	-2.321	.018	.034	3	1
UCEC	INPP4B →	-0.323	-3.169	.026	.018	3	1
UCEC	mTOR_pS2448 →	-0.135	-2.000	.045	.032	3	1
UCEC	PCNA →	+0.212	+2.000	.029	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MEK1 by CWF19L1 expression — UCEC

Explore this box plot interactively →