CWC25

Across TCGA pan-cancer cohorts, CWC25 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CWC25 data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher CWC25 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CWC25 expression acts as an unfavorable survival marker.

LGG and SKCM are the cancer types where CWC25 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Median	All	0.324	0.811	.012	6	view →
SKCM	OS	Median	III,IV	0.269	0.701	.015	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CWC25–LGG (OS)

Open the LGG breakdown →