CWC25

Across TCGA pan-cancer cohorts, CWC25 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CWC25 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CWC25 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CWC25 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where CWC25 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	IV	0.887	0.198	.024	13	view →
LSCC	OS	Quartile	II,III,IV	1.000	0.589	.020	8	view →
LUAD	OS	Tertile	II,III,IV	0.829	0.462	.018	7	view →
HNSC	OS	Median	All	1.000	0.956	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CWC25–CCRCC (DFS)

Open the CCRCC breakdown →