CWC25

Across TCGA cell cohorts, CWC25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,753 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CWC25-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Nuclear export, and Chiasma assembly. Each is linked with CWC25 in more than 14 cancer types. Because this analysis shows association rather than direction, both CWC25-to-partner and partner-to-CWC25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by CWC25-low versus CWC25-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CWC25→partner) and Y-score (partner→CWC25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.063	+0.618	<.001	.004	3	15
SOFT_TISSUE	Nuclear export →	+0.108	+0.820	<.001	<.001	3	14
CNS	Chiasma assembly →	+0.153	+0.513	<.001	<.001	3	14
BONE	Microtubule polymerization →	+0.125	+0.686	.002	.004	3	13
BONE	Microtubule nucleation →	+0.105	+0.577	.005	.003	3	13
SOFT_TISSUE	Heterochromatin organization →	+0.071	+0.628	<.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,753 associations by consensus.

Negative regulation of gene expression, epigenetic by CWC25 expression — SOFT_TISSUE

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