CWC22

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CWC22 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,704 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CWC22-associated proteins across cancer lineages are HNRNPA3, U2AF2, and TSN. Each is linked with CWC22 in more than 5 cancer types. Because this analysis shows association rather than direction, both CWC22-to-partner and partner-to-CWC22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CWC22 versus HNRNPA3 in LSCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CWC22→partner) and Y-score (partner→CWC22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCHNRNPA3 →+0.253+0.502<.001<.00136
GBMU2AF2 →+0.249+0.294<.001<.00135
UCECTSN →+0.329+0.480<.001<.00135
PDACCPSF3 →+0.237+0.317<.001.00135
UCECBCAP31 →-0.781-0.347<.001<.00134
LSCCMAP2 →+0.836+0.412<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,704 associations by consensus.

CWC22 vs HNRNPA3 — LSCC

Per-sample scatter of CWC22 vs HNRNPA3 in LSCC (Pearson r = 0.42).

Explore this scatter interactively →

Exploration