CWC22

Across TCGA cell cohorts, CWC22 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,013 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CWC22-associated GO terms across cancer lineages are Nuclear pore organization, DNA-templated DNA replication, and Chromosome segregation. Each is linked with CWC22 in more than 16 cancer types. Because this analysis shows association rather than direction, both CWC22-to-partner and partner-to-CWC22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by CWC22-low versus CWC22-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CWC22→partner) and Y-score (partner→CWC22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear pore organization →	+0.136	+0.476	.005	.002	3	17
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.091	+0.568	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Chromosome segregation →	+0.115	+0.872	.002	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle process →	+0.107	+0.861	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Recombinational repair →	+0.110	+0.845	<.001	<.001	3	16
BONE	Mitochondrial RNA modification →	+0.154	+0.684	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,013 associations by consensus.

Nuclear pore organization by CWC22 expression — BONE

Explore this box plot interactively →