CUZD1

Across TCGA cell cohorts, CUZD1 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CUZD1-associated genes across cancer lineages are PRKAG3, KAAG1, and DCLK3. Each is linked with CUZD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CUZD1-to-partner and partner-to-CUZD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRKAG3 grouped by CUZD1-low versus CUZD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUZD1→partner) and Y-score (partner→CUZD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PRKAG3 →	+0.018	+3.551	.006	.009	3	1
BLOOD_Leukemia	KAAG1 →	+0.103	+3.855	<.001	.007	3	1
BLOOD_Leukemia	DCLK3 →	+0.222	+3.769	<.001	.008	3	1
BLOOD_Leukemia	WFDC12 →	+0.198	+3.874	<.001	.005	3	1
BLOOD_Leukemia	CTRB2 →	+0.070	+3.855	.006	.007	3	1
BLOOD_Leukemia	DEFB4A →	+0.096	+4.269	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

PRKAG3 by CUZD1 expression — BLOOD_Leukemia

Explore this box plot interactively →