CUX2P1

Across TCGA patient cohorts, CUX2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,274 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CUX2P1-associated GO terms across cancer lineages are Negative regulation of actin filament polymerization, Positive regulation of transmembrane transport, and Actin polymerization or depolymerization. Each is linked with CUX2P1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CUX2P1-to-partner and partner-to-CUX2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of actin filament polymerization grouped by CUX2P1-low versus CUX2P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CUX2P1→partner) and Y-score (partner→CUX2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of actin filament polymerization →	+0.091	+0.128	<.001	<.001	3	7
STAD	Positive regulation of transmembrane transport →	+0.060	+0.151	<.001	<.001	3	7
ESCA	Actin polymerization or depolymerization →	+0.098	+0.112	<.001	.001	3	6
STAD	Regulation of peptide transport →	+0.062	+0.118	<.001	<.001	3	6
ESCA	Regulation of postsynapse organization →	+0.083	+0.213	<.001	<.001	3	6
ESCA	Negative regulation of autophagy →	+0.111	+0.142	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,274 associations by consensus.

Negative regulation of actin filament polymerization by CUX2P1 expression — STAD

Explore this box plot interactively →