CUX2

Across TCGA patient cohorts, CUX2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,822 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CUX2-associated proteins across cancer lineages are TBRG4, CELF2, and GNG2. Each is linked with CUX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CUX2-to-partner and partner-to-CUX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUX2 versus TBRG4 in HNSC, with a Pearson correlation of -0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CUX2→partner) and Y-score (partner→CUX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TBRG4 →	-0.392	-0.287	<.001	.005	3	4
HNSC	CELF2 →	+0.521	+0.297	<.001	<.001	3	4
GBM	GNG2 →	+0.856	+1.205	<.001	<.001	3	4
CCRCC	PACSIN1 →	+0.959	+0.060	.007	.004	3	4
GBM	MYO1E →	-0.377	-0.653	<.001	<.001	3	3
GBM	PLCL1 →	+0.476	+0.639	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,822 associations by consensus.

CUX2 vs TBRG4 — HNSC

Explore this scatter interactively →