CUX2

Across TCGA patient cohorts, CUX2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,176 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CUX2-associated genes across cancer lineages are MCM5, RASD2, and AQP9. Each is linked with CUX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CUX2-to-partner and partner-to-CUX2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUX2 versus MCM5 in LUAD, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUX2→partner) and Y-score (partner→CUX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MCM5 →	+1.392	+1.239	.005	.006	3	1
LUAD	RASD2 →	+1.609	+1.710	<.001	.002	3	1
LUAD	AQP9 →	+1.496	+1.536	.008	.007	3	1
LUAD	MEGF8 →	+1.673	+1.503	.001	.007	3	1
LUAD	CCDC114 →	+2.023	+1.476	.003	.009	3	1
LUAD	AHR →	+0.976	+1.239	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,176 associations by consensus.

CUX2 vs MCM5 — LUAD

Explore this scatter interactively →