CUX1

Across TCGA patient cohorts, CUX1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,891 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CUX1-associated genes across cancer lineages are SRPK2, PPFIA1, and GTF2I. Each is linked with CUX1 in more than 33 cancer types. Because this analysis shows association rather than direction, both CUX1-to-partner and partner-to-CUX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUX1 versus SRPK2 in ACC, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUX1→partner) and Y-score (partner→CUX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	SRPK2 →	+1.101	+0.876	<.001	<.001	3	34
UVM	PPFIA1 →	+1.200	+0.742	<.001	<.001	3	34
THYM	GTF2I →	+1.768	+0.739	<.001	<.001	3	33
ACC	GSK3B →	+0.839	+0.819	<.001	<.001	3	33
KICH	TMEM245 →	+1.201	+0.836	<.001	<.001	3	33
DLBC	USP34 →	+2.072	+1.277	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,891 associations by consensus.

CUX1 vs SRPK2 — ACC

Explore this scatter interactively →