CUX1

Across TCGA patient cohorts, CUX1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,750 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CUX1-associated genes across cancer lineages are PPP1R16B, KLRD1, and PRKCB. Each is linked with CUX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CUX1-to-partner and partner-to-CUX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUX1 versus PPP1R16B in GBM, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUX1→partner) and Y-score (partner→CUX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PPP1R16B →	-1.309	-0.206	.002	<.001	3	5
HNSC	KLRD1 →	-0.688	-0.196	<.001	.006	3	5
LSCC	PRKCB →	-0.745	-0.267	.001	.001	3	5
HNSC	SMURF1 →	+0.672	+0.252	<.001	<.001	3	5
HNSC	TBL2 →	+0.477	+0.256	<.001	<.001	3	5
HNSC	MDH2 →	+0.574	+0.254	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,750 associations by consensus.

CUX1 vs PPP1R16B — GBM

Explore this scatter interactively →