CUTA

Across TCGA pan-cancer cohorts, CUTA mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CUTA data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher CUTA mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CUTA expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

UCEC, HNSC, and LSCC are the cancer types where CUTA mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.433	1.000	.007	12	view →
HNSC	DFS	Tertile	II,III,IV	0.428	0.736	.015	11	view →
LSCC	DFS	Tertile	II,III,IV	0.815	0.984	.034	5	view →
LUAD	OS	Tertile	III,IV	0.640	1.000	.013	4	view →
PDAC	OS	Quartile	III,IV	0.977	0.461	.016	2	view →
CCRCC	OS	Median	All	1.000	0.687	.018	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CUTA–UCEC (OS)

Open the UCEC breakdown →