CUL7

Across TCGA patient cohorts, CUL7 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,458 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CUL7-associated proteins across cancer lineages are XPO5, HNRNPLL, and ZNF318_S1243. Each is linked with CUL7 in more than 4 cancer types. Because this analysis shows association rather than direction, both CUL7-to-partner and partner-to-CUL7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUL7 versus XPO5 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL7→partner) and Y-score (partner→CUL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	XPO5 →	+0.511	+0.498	<.001	<.001	3	5
HNSC	HNRNPLL →	+0.203	+0.635	.002	.001	3	4
LSCC	ZNF318_S1243 →	+0.441	+0.409	<.001	.002	3	4
LSCC	ZNF318_S2101 →	+0.475	+0.377	.001	.002	3	4
LSCC	NUP153 →	+0.234	+0.535	<.001	.001	3	4
OV	PTK7 →	+0.527	+0.846	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,458 associations by consensus.

CUL7 vs XPO5 — LSCC

Explore this scatter interactively →