CUL7

Across TCGA patient cohorts, CUL7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,077 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CUL7-associated genes across cancer lineages are CCDC8, CALU, and GPC6. Each is linked with CUL7 in more than 4 cancer types. Because this analysis shows association rather than direction, both CUL7-to-partner and partner-to-CUL7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUL7 versus CCDC8 in UCEC, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL7→partner) and Y-score (partner→CUL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC8 →	+1.198	+0.356	<.001	<.001	3	5
GBM	CALU →	+0.595	+0.342	<.001	<.001	3	5
HNSC	GPC6 →	+0.989	+0.194	<.001	<.001	3	4
COAD	PLPP4 →	+1.167	+0.489	.004	.007	3	4
COAD	FBXO17 →	+0.868	+0.545	<.001	.008	3	4
LSCC	RN7SL526P →	+0.820	+0.301	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,077 associations by consensus.

CUL7 vs CCDC8 — UCEC

Explore this scatter interactively →