CUL7

Across TCGA cell cohorts, CUL7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,090 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CUL7-associated GO terms across cancer lineages are Golgi to plasma membrane transport, Cilium movement involved in cell motility, and Cilium or flagellum-dependent cell motility. Each is linked with CUL7 in more than 14 cancer types. Because this analysis shows association rather than direction, both CUL7-to-partner and partner-to-CUL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to plasma membrane transport grouped by CUL7-low versus CUL7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL7→partner) and Y-score (partner→CUL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Golgi to plasma membrane transport →	+0.094	+1.120	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.097	-1.091	<.001	<.001	3	15
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.098	-1.372	.003	.004	2	15
UPPER_AERODIGESTIVE_TRACT	Regulation of autophagosome maturation →	+0.107	+1.465	<.001	<.001	3	14
STOMACH	Golgi to plasma membrane protein transport →	+0.155	+1.139	<.001	<.001	2	15
OESOPHAGUS	Cilium-dependent cell motility →	-0.098	-1.372	.003	.004	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,090 associations by consensus.

Golgi to plasma membrane transport by CUL7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →