CUL3

Across TCGA cell cohorts, CUL3 RNA expression is significantly associated with the RNA expression of many other genes, with 9,890 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CUL3-associated genes across cancer lineages are XRCC5, SUMO1, and FASTKD2. Each is linked with CUL3 in more than 19 cancer types. Because this analysis shows association rather than direction, both CUL3-to-partner and partner-to-CUL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CUL3 versus XRCC5 in BLOOD_Myeloma, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUL3→partner) and Y-score (partner→CUL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	XRCC5 →	+1.001	+0.755	<.001	<.001	3	20
LUNG_NSCLC_LUSC	SUMO1 →	+1.086	+0.657	<.001	<.001	3	18
BLOOD_Myeloma	FASTKD2 →	+1.067	+0.971	<.001	<.001	3	17
BLOOD_Myeloma	PSMD1 →	+0.967	+0.623	<.001	<.001	3	17
BLOOD_Lymphoma	NCL →	+1.062	+0.667	<.001	<.001	3	16
BLOOD_Myeloma	CNOT9 →	+0.979	+0.639	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,890 associations by consensus.

CUL3 vs XRCC5 — BLOOD_Myeloma

Explore this scatter interactively →