CUEDC2

Across TCGA pan-cancer cohorts, CUEDC2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CUEDC2 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CUEDC2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CUEDC2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where CUEDC2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.557	0.927	<.001	47	view →
HNSC	DFS	Median	IV	0.876	0.532	.007	9	view →
LUAD	DFS	Quartile	II,III,IV	0.181	0.660	.041	5	view →
UCEC	DFS	Tertile	III,IV	1.000	0.532	.042	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CUEDC2–CCRCC (DFS)

Open the CCRCC breakdown →