CUEDC2

Across TCGA cell cohorts, CUEDC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,351 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CUEDC2-associated GO terms across cancer lineages are D-amino acid metabolic process, Ornithine metabolic process, and Regulation of smoothened signaling pathway. Each is linked with CUEDC2 in more than 10 cancer types. Because this analysis shows association rather than direction, both CUEDC2-to-partner and partner-to-CUEDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, D-amino acid metabolic process grouped by CUEDC2-low versus CUEDC2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CUEDC2→partner) and Y-score (partner→CUEDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	D-amino acid metabolic process →	+1.307	+0.892	<.001	<.001	3	10
LUNG_SCLC	Ornithine metabolic process →	+0.125	+0.803	.005	<.001	3	10
OVARY	Regulation of smoothened signaling pathway →	+0.039	+0.704	.008	<.001	2	11
OVARY	Mitochondrial DNA repair →	+0.108	+0.714	<.001	.001	3	9
LIVER	AMP biosynthetic process →	+0.162	+1.322	<.001	<.001	3	9
OVARY	Intermediate filament-based process →	-0.132	-0.608	.007	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,351 associations by consensus.

D-amino acid metabolic process by CUEDC2 expression — LUNG_SCLC

Explore this box plot interactively →