CUEDC2

Across TCGA cell cohorts, CUEDC2 mutation is significantly associated with the mutation status of many other genes, with 1,614 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CUEDC2-associated genes across cancer lineages are HOXA1, DPF1, and SYT7. Each is linked with CUEDC2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CUEDC2-to-partner and partner-to-CUEDC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXA1 grouped by CUEDC2-low versus CUEDC2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CUEDC2→partner) and Y-score (partner→CUEDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HOXA1 →	+5.321	+5.894	.002	.002	1	3
BLOOD_Leukemia	DPF1 →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	SYT7 →	+6.321	+6.321	.001	.001	1	3
BLOOD_Leukemia	GNA11 →	+4.736	+5.560	.003	.003	1	3
BLOOD_Leukemia	PPARD →	+4.000	+5.050	.008	.008	1	3
LARGE_INTESTINE	SGCE →	+4.087	+5.044	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,614 associations by consensus.

HOXA1 by CUEDC2 expression — BLOOD_Leukemia

Explore this box plot interactively →