CUEDC1

Across TCGA pan-cancer cohorts, CUEDC1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CUEDC1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher CUEDC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CUEDC1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

LSCC, LUAD, and UCEC are the cancer types where CUEDC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Tertile	All	0.912	1.000	.006	16	view →
LUAD	DFS	Tertile	All	0.833	0.976	.001	16	view →
UCEC	DFS	Median	II,III,IV	0.923	0.503	.006	12	view →
PDAC	DFS	Median	III,IV	0.975	0.487	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CUEDC1–LSCC (DFS)

Open the LSCC breakdown →