Q-omics provides the consensus-scored CUBNP3 profile across patient tissues and cancer cell-line models. CUBNP3 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, CUBNP3 is differentially expressed in 6, with the highest sampling consensus in KIRP. Additionally, CUBNP3 RNA expression shows 6,594 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, KIRP, and STAD as cancer lineages where CUBNP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CUBNP3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CUBNP3 survival associations across molecular data types. CUBNP3 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CUBNP3 RNA expression–survival associations across cancer types. High CUBNP3 expression shows unfavorable associations in KICH, LUAD, TGCT and CHOL, but favorable associations in KIRC and MESO. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for CUBNP3 RNA expression.
This table summarizes CUBNP3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for CUBNP3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CUBNP3 shows lower tumor expression in KIRP, KICH and BRCA and higher tumor expression in KIRC, LUSC and LIHC. The KIRP box plot shows higher CUBNP3 RNA expression in normal versus tumor tissue (log2 FC = −0.194, t-test p < 0.001).
This table shows molecular features associated with CUBNP3 in patient tissues and cancer cell lines. In patient samples, CUBNP3 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
