CUBNP2

Across TCGA pan-cancer cohorts, CUBNP2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CUBNP2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CUBNP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CUBNP2 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

KIRC, BRCA, and LUSC are the cancer types where CUBNP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CUBNP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.045	<.001	9	view →
BRCA	Female	All	+0.031	.009	4	view →
LUSC	Male	All	+0.076	.001	3	view →
PRAD	All	All	+0.049	<.001	2	view →
KIRP	All	III,IV	−0.042	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

CUBNP2–KIRC

Open the KIRC breakdown →