CTXN2

Across TCGA patient cohorts, CTXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,975 significant associations in total. LGG shows the largest number of these associations.

The most reproducible CTXN2-associated GO terms across cancer lineages are Tetrapyrrole biosynthetic process, Microtubule-based transport, and RNA 3'-end processing. Each is linked with CTXN2 in more than 16 cancer types. Because this analysis shows association rather than direction, both CTXN2-to-partner and partner-to-CTXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tetrapyrrole biosynthetic process grouped by CTXN2-low versus CTXN2-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTXN2→partner) and Y-score (partner→CTXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Tetrapyrrole biosynthetic process →	+0.064	+0.017	<.001	.001	3	17
STAD	Microtubule-based transport →	+0.041	+0.048	<.001	.001	2	17
ESCA	RNA 3'-end processing →	+0.073	+0.044	<.001	.002	3	16
ESCA	mRNA 3'-end processing →	+0.076	+0.047	<.001	.001	3	16
ESCA	Protein localization to microtubule organizing center →	+0.062	+0.037	<.001	.002	3	16
STAD	Cerebral cortex development →	+0.047	+0.053	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,975 associations by consensus.

Tetrapyrrole biosynthetic process by CTXN2 expression — LAML

Explore this box plot interactively →