CTXN2

Across TCGA patient cohorts, CTXN2 mutation is significantly associated with the RNA expression of many other genes, with 2,688 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTXN2-associated genes across cancer lineages are LINC00458, LINC01072, and LINC02559. Each is linked with CTXN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CTXN2-to-partner and partner-to-CTXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00458 grouped by CTXN2-low versus CTXN2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTXN2→partner) and Y-score (partner→CTXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00458 →	+0.484	+4.653	<.001	.004	3	2
CESC	LINC01072 →	+0.224	+5.345	<.001	.001	3	2
CESC	LINC02559 →	+1.329	+5.342	<.001	.002	3	2
CESC	ACSL6-AS1 →	+0.104	+5.569	<.001	.002	3	2
UCEC	STAG3L4 →	+0.612	+4.021	<.001	<.001	3	2
UCEC	EDF1 →	+0.392	+1.617	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,688 associations by consensus.

LINC00458 by CTXN2 expression — CESC

Explore this box plot interactively →