CTXN2

Across TCGA cell cohorts, CTXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,145 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTXN2-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Regulation of syncytium formation by plasma membrane fusion, and Negative regulation of myoblast fusion. Each is linked with CTXN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both CTXN2-to-partner and partner-to-CTXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by CTXN2-low versus CTXN2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTXN2→partner) and Y-score (partner→CTXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Mitochondrial electron transport, cytochrome c to oxygen →	+0.063	+0.037	<.001	.001	3	8
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.106	+0.316	<.001	.002	3	7
BLOOD_Leukemia	Negative regulation of myoblast fusion →	+0.055	+0.022	<.001	.008	3	7
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.046	+0.020	<.001	.004	3	7
OVARY	Oxidative phosphorylation →	+0.085	+0.042	<.001	<.001	3	7
OVARY	Proton motive force-driven ATP synthesis →	+0.106	+0.060	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,145 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by CTXN2 expression — OVARY

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