CTU2

Across TCGA patient cohorts, CTU2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,541 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CTU2-associated genes across cancer lineages are NIP7, CATSPERE, and CCNB2. Each is linked with CTU2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CTU2-to-partner and partner-to-CTU2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTU2 versus NIP7 in BRCA, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTU2→partner) and Y-score (partner→CTU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NIP7 →	+0.538	+0.259	<.001	<.001	3	4
UCEC	CATSPERE →	-0.727	-0.202	<.001	.001	3	4
BRCA	CCNB2 →	+0.930	+0.268	<.001	<.001	3	4
BRCA	NUTF2 →	+0.436	+0.228	<.001	<.001	3	4
HNSC	POLR2C →	+0.381	+0.185	<.001	.001	3	4
BRCA	USP10 →	+0.584	+0.374	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,541 associations by consensus.

CTU2 vs NIP7 — BRCA

Explore this scatter interactively →