CTU2

Across TCGA cell cohorts, CTU2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,409 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CTU2-associated GO terms across cancer lineages are tRNA thio-modification, tRNA wobble position uridine thiolation, and Protein urmylation. Each is linked with CTU2 in more than 17 cancer types. Because this analysis shows association rather than direction, both CTU2-to-partner and partner-to-CTU2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA thio-modification grouped by CTU2-low versus CTU2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTU2→partner) and Y-score (partner→CTU2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	tRNA thio-modification →	+0.147	+0.899	<.001	<.001	3	18
LIVER	tRNA wobble position uridine thiolation →	+0.126	+0.975	<.001	.003	3	17
LUNG_NSCLC_LUSC	Protein urmylation →	+0.089	+0.833	<.001	<.001	3	16
OESOPHAGUS	Mitochondrial large ribosomal subunit assembly →	+0.178	+0.931	<.001	<.001	3	16
BLOOD_Myeloma	Ribosomal large subunit assembly →	+0.117	+0.920	.002	.003	3	15
OESOPHAGUS	rRNA metabolic process →	+0.177	+0.930	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,409 associations by consensus.

tRNA thio-modification by CTU2 expression — URINARY_TRACT

Explore this box plot interactively →