CTTNBP2NL

Across TCGA patient cohorts, CTTNBP2NL mutation is significantly associated with the RNA expression of many other genes, with 4,866 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTTNBP2NL-associated genes across cancer lineages are LETM1, ENO1, and IER3IP1. Each is linked with CTTNBP2NL in more than 2 cancer types. Because this analysis shows association rather than direction, both CTTNBP2NL-to-partner and partner-to-CTTNBP2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LETM1 grouped by CTTNBP2NL-low versus CTTNBP2NL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTNBP2NL→partner) and Y-score (partner→CTTNBP2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LETM1 →	+0.588	+2.686	<.001	<.001	3	3
UCEC	ENO1 →	+0.500	+3.103	.002	<.001	3	3
UCEC	IER3IP1 →	+0.374	+2.431	.006	.001	3	3
HNSC	RNU6-206P →	+0.361	+6.357	<.001	<.001	3	2
UCEC	TMEM138 →	+0.227	+1.949	.004	.001	3	2
UCEC	CCDC15 →	+0.489	+1.970	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,866 associations by consensus.

LETM1 by CTTNBP2NL expression — UCEC

Explore this box plot interactively →