CTTNBP2NL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CTTNBP2NL mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTTNBP2NL-associated genes across cancer lineages are CLUAP1, MS4A4A, and CCL21. Each is linked with CTTNBP2NL in more than 1 cancer types. Because this analysis shows association rather than direction, both CTTNBP2NL-to-partner and partner-to-CTTNBP2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLUAP1 grouped by CTTNBP2NL-low versus CTTNBP2NL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTNBP2NL→partner) and Y-score (partner→CTTNBP2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECLUAP1 →+0.642+3.215.006.00931
LARGE_INTESTINEMS4A4A →+0.144+2.678<.001.00331
LARGE_INTESTINECCL21 →+0.045+2.560<.001.00831
LARGE_INTESTINEFAM124A →+0.701+3.295.001.00631
LARGE_INTESTINESBSPON →+1.787+3.302<.001.00831
LARGE_INTESTINEOR2B2 →+0.022+2.669.004.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CLUAP1 by CTTNBP2NL expression — LARGE_INTESTINE

Box plot of CLUAP1 in CTTNBP2NL-low vs CTTNBP2NL-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration