CTTNBP2NL

Across TCGA cell cohorts, CTTNBP2NL mutation is significantly associated with the mutation status of many other genes, with 3,576 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CTTNBP2NL-associated genes across cancer lineages are SEC62, CCNL1, and AP1G1. Each is linked with CTTNBP2NL in more than 2 cancer types. Because this analysis shows association rather than direction, both CTTNBP2NL-to-partner and partner-to-CTTNBP2NL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SEC62 grouped by CTTNBP2NL-low versus CTTNBP2NL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTNBP2NL→partner) and Y-score (partner→CTTNBP2NL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SEC62 →	+3.632	+2.874	.002	.002	1	3
BLOOD_Leukemia	CCNL1 →	+5.894	+5.321	.002	.002	1	3
BLOOD_Leukemia	AP1G1 →	+4.479	+5.635	<.001	<.001	1	3
BLOOD_Leukemia	SOST →	+4.894	+4.894	.004	.004	1	3
BLOOD_Leukemia	IBA57 →	+4.309	+4.560	.007	.007	1	3
LARGE_INTESTINE	BCL7C →	+2.369	+2.471	.005	.005	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,576 associations by consensus.

SEC62 by CTTNBP2NL expression — LARGE_INTESTINE

Explore this box plot interactively →