CTTN

Across TCGA patient cohorts, CTTN protein abundance is significantly associated with the RNA expression of many other genes, with 9,991 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CTTN-associated genes across cancer lineages are RIPOR2, LAX1, and PREX1. Each is linked with CTTN in more than 3 cancer types. Because this analysis shows association rather than direction, both CTTN-to-partner and partner-to-CTTN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTTN versus RIPOR2 in GBM, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTTN→partner) and Y-score (partner→CTTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RIPOR2 →	-0.656	-0.167	<.001	.001	3	4
HNSC	LAX1 →	-0.916	-0.538	.001	<.001	3	4
HNSC	PREX1 →	-0.686	-0.486	<.001	<.001	3	4
HNSC	ANO1 →	+1.672	+0.689	<.001	<.001	3	4
HNSC	LTO1 →	+1.052	+0.749	<.001	<.001	3	4
CCRCC	SLAMF6 →	-0.837	-0.186	.001	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,991 associations by consensus.

CTTN vs RIPOR2 — GBM

Explore this scatter interactively →