CTSV

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CTSV RNA expression is significantly associated with the go_rna of many other GO terms, with 4,256 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CTSV-associated GO terms across cancer lineages are Nuclear pore complex assembly, Fat cell proliferation, and Negative regulation of mRNA catabolic process. Each is linked with CTSV in more than 8 cancer types. Because this analysis shows association rather than direction, both CTSV-to-partner and partner-to-CTSV results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by CTSV-low versus CTSV-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSV→partner) and Y-score (partner→CTSV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUENuclear pore complex assembly →+0.132+2.165<.001<.00139
SOFT_TISSUEFat cell proliferation →-0.211-1.679<.001<.00139
CNSNegative regulation of mRNA catabolic process →+0.047+1.373.001.00239
LIVERRegulation of AV node cell action potential →+1.489+2.334.002<.00138
CNSCardiac muscle cell-cardiac muscle cell adhesion →+0.685+1.291.004.00138
UPPER_AERODIGESTIVE_TRACTAntigen processing and presentation of exogenous peptide antigen via MHC class II →+0.155+0.975.001.00238
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,256 associations by consensus.

Nuclear pore complex assembly by CTSV expression — SOFT_TISSUE

Box plot of Nuclear pore complex assembly in CTSV-low vs CTSV-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration