CTSS

Across TCGA patient cohorts, CTSS RNA expression is significantly associated with the protein abundance of many other proteins, with 21,947 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTSS-associated proteins across cancer lineages are LCP1, LCP2, and SASH3. Each is linked with CTSS in more than 9 cancer types. Because this analysis shows association rather than direction, both CTSS-to-partner and partner-to-CTSS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSS versus LCP1 in GBM, with a Pearson correlation of 0.86.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSS→partner) and Y-score (partner→CTSS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCP1 →	+1.050	+1.498	<.001	<.001	3	10
HNSC	LCP2 →	+0.746	+1.430	<.001	<.001	3	10
GBM	SASH3 →	+0.679	+1.491	<.001	<.001	3	10
HNSC	FNBP1 →	+0.599	+1.085	<.001	.001	3	10
GBM	FYB1 →	+0.938	+1.467	<.001	<.001	3	10
GBM	WIPF1 →	+0.465	+1.375	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,947 associations by consensus.

CTSS vs LCP1 — GBM

Explore this scatter interactively →