CTSO

Across TCGA patient cohorts, CTSO RNA expression is significantly associated with the protein abundance of many other proteins, with 21,264 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CTSO-associated proteins across cancer lineages are ILK, CLPX, and NOL10. Each is linked with CTSO in more than 7 cancer types. Because this analysis shows association rather than direction, both CTSO-to-partner and partner-to-CTSO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTSO versus ILK in UCEC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSO→partner) and Y-score (partner→CTSO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ILK →	+0.481	+0.565	<.001	<.001	3	8
LSCC	CLPX →	-0.297	-0.756	<.001	<.001	3	8
BRCA	NOL10 →	-0.372	-0.776	<.001	<.001	3	8
BRCA	PALLD →	+0.663	+0.811	<.001	<.001	3	8
LUAD	RPL12_S38 →	-1.147	-0.592	<.001	<.001	3	7
LUAD	RRP36_S73 →	-0.847	-0.768	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,264 associations by consensus.

CTSO vs ILK — UCEC

Explore this scatter interactively →