CTSLP4

Across TCGA pan-cancer cohorts, CTSLP4 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CTSLP4’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CTSLP4 RNA is repressed in tumor relative to normal tissue. In most cancer types CTSLP4 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and KICH are the cancer types where CTSLP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CTSLP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.047	<.001	11	view →
THCA	All	III,IV	−0.434	<.001	8	view →
KICH	All	II,III,IV	−0.080	<.001	7	view →
HNSC	Male	All	+0.012	.039	2	view →
KIRP	All	All	−0.040	.032	1	view →
LIHC	All	All	+0.024	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CTSLP4–KIRC

Open the KIRC breakdown →