Across TCGA pan-cancer cohorts, CTSL3P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CTSL3P data layer compared with 11 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CTSL3P Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CTSL3P expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SKCM and UCEC are the cancer types where CTSL3P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	All	0.054	0.739	<.001	12	view →
UCEC	DFS	Median	III,IV	1.000	0.543	.044	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: CTSL3P tumor-vs-normal RNA expression · all CTSL3P data types