Across TCGA patient cohorts, CTSL3P mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CTSL3P-associated genes across cancer lineages are Rictor_pT1135, eEF2, and ERK2. Each is linked with CTSL3P in more than 1 cancer types. Because this analysis shows association rather than direction, both CTSL3P-to-partner and partner-to-CTSL3P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTSL3P→partner) and Y-score (partner→CTSL3P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rictor_pT1135 →	-0.123	-3.169	.010	.018	3	2
UCEC	eEF2 →	+0.470	+2.999	.004	.035	3	1
UCEC	ERK2 →	+0.307	+2.999	<.001	.035	3	1
UCEC	FOXO3a_pS318_S321 →	-0.134	-3.449	.020	.005	3	1
UCEC	Gab2 →	+0.496	+3.321	.002	.010	3	1
UCEC	GAPDH →	+0.634	+2.999	.011	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

CTSL3P survival (RNA) · tumor vs normal (RNA) · all CTSL3P data types